Find Out Why You Should Take Water-Soluble Pumpkin Seed Extract with Soybean Germ Extract for Overactive Bladder.

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Pumpkin Seeds (Creative Commons by FoodDistaBlog)

You Can Do Something About Overactive Bladder!

When patients consult allopathic medical practitioners for bladder problems, they may be prescribed drugs, which often are not that effective. These medicines carry side effects that may cause other problems and can be expensive. Rather than seek treatment, many people just assume that urinary problems are related to aging, and there is nothing to be done about them. Unfortunately, the effect not only on quality of life but on broken sleep can cause other disease conditions including hypertension. However, studies that took place in the 1990s and the first decade of the 21st century in Japan offer some hope through herbal remedies. For centuries before these reports some South American people used pumpkin seeds for urinary problems as a folk medicine. One Japanese study looked at adding water-soluble pumpkin seed extract and soybean germ extract to processed foods1. After six weeks there was a significant decrease of urination frequency during the night. There were some side effects in 14 patients related to an increase in testosterone. After cessation of the treatment several of these patients did revert to previous levels of testosterone after 2 to 4 months. The study authors felt the other increases were not related to the treatment. Nevertheless, this is a cautionary element.

Try Pumpkin Seed Extract to Reduce Nocturnal Need to Urinate

While overactive bladders happen predominantly in women, men do suffer bladder problems, usually related to prostate problems such as benign enlargement of the gland. Even when treated with drugs continual nightly wake ups in order to urinate remain with a number of men. One of the drugs used to treat overgrowth of the prostate gland inhibits an enzyme called 5-alpha reductase. Researchers tested a water- soluble pumpkin seed extract in vitro (test tube). The extract inhibited 5-alpha reductase by 50% 2. The other factor often involved with prostate hypertrophy is an enzyme called aromatase, which converts testosterone into estradiol. In the same study water-soluble pumpkin seed extract reduced estradiol by 50%.

There is even stronger data supporting the efficacy of water-soluble pumpkin seed extract in helping women who suffer frequent urination or incontinence. Three different Japanese studies found similar positive benefits. After eight weeks daily urinations went from 9.3 to 5.6. Average nighttime urinations dropped from 2.0 to 0.8 Average incontinent episodes of 2.3 every day after eight weeks of treatment declined to one per day. Each of the three studies was on small groups. The first had 39 postmenopausal women, the second 50 and the third only ten. Because of these small numbers larger and well controlled studies are needed before final conclusions are possible about the value of water-soluble pumpkin seed extract combined with soy bean germ extract.

Available Products

Japanese researchers patented a pumpkin seed extract called EFLA940. In Sweden a product called Uretin 45+ also containing water-soluble pumpkin seed extract combined with soy bean germ extract had similar positive results in a very small sample of women. Researchers gave ten postmenopausal women tablets containing 87.5 mg Cucurbitae seed extract EFLA940 and 16.6 mg soybean germ extract (PEP). After eight weeks the number of nocturnal urinary episodes dropped from 3.3 to 2.03.

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Notes

1 Sogabe Hitoshi and Terado Takashi, “Clinical study of mixed processed foods containing of pumpkin seed extract and soybean germ extract on pollakiuria in night in elder women.” Japanese Journal of Medicine and Pharmaceutical Science 2001 46:5: 727-737.

2https://www.helhetsdoktorn.nu/EFLA940Pumpkin02-04.pdf Accessed 23 November 2008.

3https://www.kvinnohalsa.se/pdf/swe_pilot.pdf Accessed 23 November 2008.