Adenosine for Pulmonary Artery Hypertension

Adenosine for Pulmonary Artery Hypertension
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Adenosine, also referred to as Adenocard IV, is prescribed to treat rapid heart action, paroxysmal supraventricular tachycardia, and supraventricular tachycardia. Doctors may also prescribe adenosine for pulmonary artery hypertension. As with all medications, patients should educate themselves on the side effects, contraindications, drug interactions, warnings, and how this medication should be administered.

How Does Adenosine Help to Treat Pulmonary Artery Hypertension?

Pulmonary artery hypertension is a potentially fatal condition in which abnormally increased blood pressure affects the pulmonary artery. Adenosine is an important building block and component of DNA.

Adenosine Administration

This medication is administered intravenously. This means that a needle and syringe are placed in a vein and the medication is pushed. The dose will depend on the patient’s age and the condition they are taking it for. At this time this medication is still in the testing stage for pulmonary artery hypertension so the best dose is still be determined.

Adenosine Side Effects

All medications have side effects and the side effects of adenosine are considered common, infrequent, or rare. They are further classified as either less severe or severe. The common side effects that are considered less severe include temporary redness of the neck and face, digestive system disorders, dizziness, and neck pain. The common side effects that are considered severe include premature atrial heartbeats, chest pain, ventricular premature heartbeats, trouble breathing, sinus tachycardia, abnormal heart rhythm, sinus bradycardia, and supraventricular cardiac arrhythmia.

All of the infrequent side effects are considered less severe. These include abnormally low blood pressure, nervousness, head pain, and numbness and tingling.

The rare side effects that are considered less severe include backache, taste problems, heart pounding or throbbing, cough, vomiting, excessive sweating, rapid deep breathing, and feeling like vomiting. The rare side effects that are considered severe include seizures, blurred vision, bronchospasm, high blood pressure, lung failure that results in loss of breath, heart block, slow heartbeat, very rapid heartbeat, and atrial fibrillation.

Adenosine Contraindications

This medication is contraindicated for patients with second or third degree AV block and sinus node disease, expect for those who have a functioning artificial pacemaker. Those who have a known sensitivity to this medication should also avoid it.

Adenosine Drug Interactions

This medication may have to be avoided if the patient is taking certain other medications. These include cardioactive drugs, digitalis, quinidine, angiotensin converting enzyme inhibitors, beta-blocking agents, digoxin, calcium channel blocking agents, verapamil, methylxanthines, dipyridamole, and carbamazepine.

Adenosine Warnings

Studies have yet to be performed on pregnant women so it is unknown whether any adverse effects would occur. It is thought that no fetal effects would occur because adenosine does occur naturally in the body.

Resources (2010). Adenosine Description. Retrieved on March 24, 2010 from

High Blood Pressure Articles. (2009). Using Adenosine for Pulmonary Hypertension. Retrieved on March 24, 2010 from:

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