Azithromycin is in the macrolide antibiotics drug group. Possible side effects of azithromycin include nausea and vomiting, diarrhea, constipation, dizziness, fatigue, headache, nervousness and insomnia, vaginal itching and discharge, skin itching or rash, ringing in ears or other hearing problems and a decreased sense of taste or smell. More serious side effects could indicate an allergic reaction.
There are many drugs that can interact with azithromycin. These include digoxin, carbamazepine, cyclosporine, phenytoin, pimozide, theophylline, triazolam and warfarin. Calcium channel blockers, medications used to lower cholesterol, ergot medications, HIV medications, other antibiotics and birth control pills can also interfere with this medication.
There is a risk of allergic reaction to this antibiotic, so people who have had allergic reactions to similar drugs, including erythromycin, clarithromycin, telithromycin and troleandomycin.