Hormone Therapy Drugs
Prostate cancer drugs include hormone therapy, which decreases the effect of testosterone on prostate cancer. Testosterone is the main male hormone which the cancer needs to grow. Hormone treatments can prevent further growth and spread of the cancer. It is primarily used to relieve symptoms in men whose cancer has spread.
The primary type of hormone therapy is called a luteinizing hormone-releasing hormones (LH-RH) agonist. These drugs keep the body from making testosterone and are given by injection, usually each three to six months. This category includes the drugs leuprolide, goserelin, nafarelin, triptorelin, histrelin, buserelin and degarelix.
Other hormone medications are called androgen-blocking drugs and they are often given along with the LH-RH agonist drugs. They include flutamide, bicalutamide and nilutamide.
Drugs that prevent the adrenal glands from making androgens are ketoconazole and aminoglutethimide. Rarely used today because of side effects are the female hormones, estrogens, which can prevent the testicles from producing testosterone.