Zoloft (Sertraline) is used to treat panic and social anxiety disorder. It is in the class of drugs called selective serotonin reuptake inhibitors (SSRIs). It works by restoring serotonin in the brain. However, drugs in this class can increase the chance of suicidal thoughts in teens.
Do not take Zoloft if you have taken an MAOI or St. Johns wort within the last 14 days.
Some medications may interact with Zoloft. They include anticoagulants, anorexiants, diuretics, Tramadol, H1 antagonist, Carbamazepine or cyproheptadine, or Aripiprazole, clozapine, digoxin, flecainide, lithium, phenytoin, pimozide, propafenone, risperidone, tricyclic antidepressants (eg. amitriptyline), or valproate (eg, valproic acid) because the risk of their side effects may be increased by Zoloft.
Side effects include constipation, diarrhea, dizziness, dry mouth, increased sweating, loss of appetite, nausea, nervousness, stomach upset, tiredness, trouble sleeping, vomiting and weight loss.
More serious side effects include allergic reactions such as hives swelling of the mouth, face lips or tongue, chest pain, black or bloody stools, fainting, fast irregular heartbeat, or new behavioral problems.