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Histamine is a chemical in the body tissues that is produced by the breakdown of histidine. It is released in allergic reactions and causes widening of capillaries, decreased blood pressure, increased release of gastric juice and tightening of the muscles of the bronchial tubes and the uterus. It creates the initial acute allergic reaction, causing itching, swelling and congestion.
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When the body is deprived of water like when it is dehydrated, a water rationing system takes effect. Histamine, which is a neurotransmitter becomes active and redistributes the water throughout the body. The histamine will go in order of circulatory priority and distribute the water first to the brain, lungs, liver, kidneys, and glands. Then, water will be sent to the muscles, bones and skin. During periods of dehydration, histamine makes sure that the vital organs have enough water to function properly. If enough water is not supplied, it must be taken from within the body. Chronic dehydration, like that which comes from chronic caffeine intoxication, can cause histamine to become excessively active and raise the levels. This may result in symptoms that may be diagnosed incorrectly as allergies, asthma, colitis, constipation, rheumatoid arthritis, and chronic pains in various parts of the body such as migraine headaches.
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High histamine can run in families and these people tend to have excessive energy and drive. They are aggressive, productive people that will drive themselves to obsession to succeed. The large histamine pools they possess cause their brain neurotransmitters to over fuel and fire excessively which causes this drive.
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Histamine levels can be decreased and symptoms relieved by daily doses of methionine, which is an amino acid that significantly detoxifies histamine. A typical adult dose is a 500 mg capsule taken four times daily. Calcium, which can be used daily morning and evening, can release additional histamine stores and lower levels in the body. When combined with magnesium, it will act as a natural tranquilizer to help prevent the insomnia that often comes with high levels of histamine.
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As with anything else, it is better to eat a healthy diet of fruits and vegetables. Try to avoid a high protein diet as most proteins contain histidine, which is the amino acid mentioned above that will synthesize even more histamine.
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