MedicineNet, in defining epididymitis, states that both doxycycline and ceftriaxone are used, if STDs are suspected, and ofloxacin may be used if the source is considered bowel microbes. Possible doxycycline side effects include fast heart rate, watery or bloody diarrhea, dizziness, blurred vision, jaundice, facial swelling and a skin rash that blisters and peels. Before taking doxycycline, tell your doctor if you have kidney or liver disease, or asthma.
Possible side effects of ceftriaxone include jaundice, confusion, watery or bloody diarrhea, white sores in the mouth, headache, nausea, dizziness, severe stomach pain, and decrease in urination. You may be unable to take ceftriaxone if you have kidney or liver disease, colitis, other stomach or intestinal disorders, or gallbladder problems.
Before taking ofloxacin, your doctor needs to know if you have myasthenia gravis, kidney or liver disease, diabetes, low potassium, epilepsy, joint problems or any reaction to an antibiotic. Possible side effects include seizure, dizziness, nausea, muscle or joint pain, restlessness, numbness or tingling in the extremities, and easy bruising.