Long-term Effects of ABVD Chemotherapy
While the short-term side effects of ABVD chemotherapy can be unpleasant to its patients, some of the long-term effects of this chemotherapy regiment can be life changing and even life threatening. Some of the long-term consequences of ABVD include:
Elevated risk of blood clots: Cancer patients have been shown to be at an elevated risk of developing blood clots or thrombosis. Furthermore, addition of chemotherapy can further enhance this risk of blood clots. Common symptoms of blood clots include pain, rash, swelling in the leg, loss of breath and chest pain.
Interactions with other medications: Certain medications, whether prescription, over-the-counter, herbal or home remedies, may interact with ABVD chemotherapy drugs and may have harmful effects. For example, ABVD patients taking diclofenac, a non-steroidal anti-inflammatory drug, have been shown to suffer from cardiac deficits, respiratory problems and bleeding.
Reproductive and developmental complications: both male and female ABVD patients have been shown to have a reduced fertility. However, ABVD has been shown to have a less likelihood of affecting fertility compared to other chemotherapy regiments given to Hodgkin lymphoma patients. Moreover, ABVD has been shown to promote irregular menstruation and even stop menstruation. While in younger women these effects are generally temporary, older women can suffer from permanent loss and thus suffer from menopausal-like symptoms.